Morning

08:00 – 08:30

Opening Ceremony

Oral presentation of Master’s and Doctoral students. (08:30 – 12:00)

Coordinators: Prof. Carlos Henrique de Castro; Prof. Rodrigo Mello Gomes

08:30 – 09:00	Amanda Silva Fernandes – Assessment of the antigenotoxic and angiogenic effects of tellimagrandin-I and camptothin-A using in vitro and in vivo assays.
09:00 – 09:30	Alessandra Gisele de Castro – Isoproterenol-induced metabolic dysfunction and pancreatic islets remodeling in Wistar rats.
09:30 – 10:00	Gessica Coelho de Souza – Evaluation of the role of naringenin on the development of benign prostatic hyperplasia in the prostate of Spontaneously Hypertensive Rats (SHR).
10:00 – 10:30	Break
10:30 – 11:00	Bárbara Gonçalves Rivello – Planning, synthesis and pharmacological evaluation of new candidates for prototypes of antitumor and antibacterial drugs, based on aplisinopsin.
11:00 – 11:30	Luana Santos Silva – Genotoxicity evaluation of Parkia platycephala lectin using different cellular levels and organisms.
11:30 – 12:00	Jhon Kennedy Alves Pereira – Planning, synthesis, and pharmacological evaluation of new candidates for neuroactive drug prototypes.

12:00 – 14:00: Lunch

Afternoon

Oral presentation of Master’s and Doctoral students. (14:00 – 16:00)

Coordinators: Prof. Elisângela de Paula Silveira Lacerda; Prof. Renata Mazaro e Costa

14:00 – 14:30	Marcos Divino Ferreira Junior – Effects of maternal exposure to glycotoxins during lactation on cardiovascular function in the offspring at adulthood.
14:30 – 15:00	Keilah Valeria Naves Cavalcante – Moderate food restriction during lactation promotes cardiovascular changes in adult wistar rats.
15:00 – 15:30	Raphaela Almeida Chiareli – Neuroprotective effect of sarcosine in an animal model of sporadic Alzheimer’s disease.
15:30 – 16:00	Lis Raquel Silva Nascimento – Evaluation of the application of ACE and ACE2 as laboratory markers in Covid-19 monitoring.
16:00 – 16:30	Break

Poster presentation (16:30 – 18:50)

Room 1 (Coordinators: Cinthia Rio Branco da Silva; Rosana Pereira Vianello)

16:30 – 16:50	Abel Vieira de Melo Bisneto – Antigenotoxic and cytotoxic effects of DvL, a lectin purified from Dioclea violacea seeds.
16:50 – 17:10	Adriano Roberto Vieira de Souza –
17:10 – 17:30	Cassio Nazareno Silva da Silva – Acetylated cashew gum-based nanoparticles loaded with essential oil presenting antifungal activity.
17:30 – 17:50	Luciana Silva Rocha Contim – Design, synthesis and pharmacological evaluation of new amiloride-like.

Room 2 (Coordinators: Ricardo Menegatti; Diego Basile Colugnati)

16:30 – 16:50	Amanda de Sá Martins de Bessa – Effects of the treatment with Compound 21, an AT2 receptor agonist, in hypertensive pregnant rats on the cardiovascular system of offspring.
16:50 – 17:10	Stéphany Vieira Brito – Effects of caffeine on the behavioral and renal function responses controlled by ghrelin.
17:10 – 17:30	Dayane de Lima Oliveira – Evaluation of the therapeutic potential of catechin hydrate in the treatment of benign prostatic hyperplasia in senile SHR rats.
17:30 – 17:50	Luana Araújo Manso – Evaluation of prostate cancer induction by testosterone in SHR rats and the effects of the association with naringenin.
17:50 – 18:10	Edvaldo Mendes Silva – Therapeutic potential of Jambu extract (Acmella oleracea), catechin hydrate and quercetin in the treatment of benign prostatic hyperplasia and prostate cancer: assays with spontaneously hypertensive rats (SHR) and RWPE-1, LNCaP and PC-3 cells.

Room 3 (Coordinators: Lee Chen Chen; Mara Rúbia Marques)

16:30 – 16:50	André Luis Batisda da Rocha – Design, synthesis and pharmacological assessment of new lead compounds to epilepsy.
16:50 – 17:10	Gustavo Almeida de Carvalho – The role of proline transporter (SLC6a7) in Alzheimer’s Disease.
17:10 – 17:30	Iara Barbosa Cabral – Trimethozine analogue (heterocyclic compound): analysis of anxiolytic activity and motor impairment.
17:30 – 17:50	Robbert Mota Pereira – Evaluation of the neuroprotective effects of the butanolic fraction of caryocar brasiliense leaves against neurotoxicity induced by 3-nitropropionic acid.

Morning

Oral presentation of Master’s students. (08:00 – 12:00)

Coordinators: Prof. Fernanda Cristina Alcantara dos Santos; Prof. Elizabeth Pereira Mendes

08:00 – 08:30	Lucas Araújo Ferreira – Maternal Early Postnatal overfeeding results in pancreatic islet remodeling and sex-specific hypothalamic insulin impairment in the adult rat offspring.
08:30 – 09:00	Nathany Ribeiro Lima dos Santos – Effects of chrysin on the development of benign prostatic hyperplasia in the ventral prostate of spontaneously hypertensive rats.
09:00 – 09:30	Raul Izidoro Ribeiro – Effect of Glyt1 inhibition on striatal damage.
09:30 – 10:00	Break
10:00 – 10:30	Romes Bittencourt Nogueira de Souza – Evaluation of ACE and ACE2 polymorphisms in the susceptibility to aggravation of covid-19.
10:30 – 11:00	Yasmin Teixeira Viana Calisto –
11:00 – 11:30	Yohanny Souza Silva – Exposure to methylglyoxal during breastfeeding causes morphological and immunohistochemical changes in the ventral prostate of young and adult male Wistar rat offspring.
11:30 – 12:00	Helen Cristian Marques Tomaz – Cardiovascular effects of angiotensin-(1-2) in spontaneously hypertensive rats.

12:00 – 14:00: Lunch

Afternoon

Session 1

Chairs: Prof. Paulo César Ghedini; Prof. Mauro Cunha Xavier Pinto

14:00 – 14:40	Prof. Andrea Tarozzi (Italy) – Oxidative stress and Nrf2-ARE pathway in neurodegenerative diseases.
14:40 – 15:20	Prof. Friederike Klempin (Germany) – Neuroplasticity of the adult mammalian hippocampus.
15:20 – 15:45	Rinaldo Rodrigues dos Passos Junior (Brazil) – Reduced O-linked N-acetyl-glucosamine (O-GlcNac) impacts on placental structure and fetal growth in spontaneously hypertensive rats.

15:45 – 16:15: Break

Session 2

Chairs: Prof. Fernanda Regina Casagrande Giachini Vitorino; Prof. James Oluwagbamigbe Fajemiroye

16:15 – 16:55	Prof. Fernanda Brusch Marinho Priviero (USA) – Innate immune system activation causes erectile dysfunction in models of metabolic disorders.
16:55 – 17:35	Prof. Anne Monique Nuyt (Canada) – Oxygen-induced cardiomyopathy in newborn rats: A model for adult cardiac diseases after preterm birth.
17:35 – 18:00	Carolina Nobre Ribeiro Pontes (Brazil) – Angiotensin-(1-7) improves cardiac left ventricular bioenergetics and mitochondrial function in a rat model of neonatal high oxygen-induced cardiomyopathy.

Morning

Session 3

Chairs: Prof. Carlos Henrique Xavier Custódio; Prof. Aline Priscila Pansani

08:00 – 08:40	Prof. Tiago Januário da Costa (Brazil/USA) – Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.
08:40 – 09:20	Prof. Simone Regina Potje (Brazil) – Glycocalyx degradation is induced by COVID-19.
09:20 – 09:45	Raiany Alves de Freitas (Brazil) – Interleukin-10 mediates anti-contractile effect of perivascular adipose tissue and vascular remodeling prevention.

09:45 – 10:15: Break

Session 4

Chairs: Prof. Jacqueline Alves Leite; Prof. Manoel Francisco Biancardi

10:15 – 10:55	Prof. Karin Lykke-Hartmann (Denmark) – Female reproduction: Challenges for infertility treatments.
10:55 – 11:35	Prof. Claudio Barbeito (Argentina) – The female prostate in the plain viscacha (Lagostomus maximus), singularities and similarities with other mammals.
11:35 – 12:15	Prof. Pal Perjesi (Hungary) – Flavonoids (chalcones) as potential antiviral (anti-SARS) agents.

Afternoon

Session 5

Chairs: Prof. Lucilene Arilho Bicudo; Dr. Isabela Pavanelli de Souza

14:00 – 14:40	Prof. Aline Petrin (USA) – Genetics and epigenetics of orofacial cleft.
14:40 – 15:20	Prof. Robert Pogue (Ireland/Brazil) – Molecular basis in genetic skeletal diseases.
15:20 – 15:45	Gisele Almeida Amaral Fonseca (Brazil) – Prednisone modifies systolic blood pressure leading to kidney injury in normotensive rats.

15:45 – 16:15: Break

Session 6

Chairs: Prof. Kátia Flávia Fernandes, Prof. Raphaela de Castro Georg

16:15 – 16:45	Prof. Karla de Aleluia Batista (Brazil) – Biological potential of proteins from beans.
16:45 – 17:15	Prof. Carlos Henrique Xavier Custódio (Brazil) – From neuronal tracers to multisystemic agents: bioactive potential of molecules from Phaseolus Vulgaris.
17:15 – 17:45	Prof. Erika Valencia Mejia (Mexico) – Antihyperglycemic and hypoglycemic activity of naturally occurring peptides and protein hydrolysates from easy-to-cook and hard-to-cook beans (Phaseolus vulgaris L.) BRS PONTAL.
17:45 – 18:10	Jefferson Hollanda Véras (Brazil) – Lactose-binding lectin from Vatairea macrocarpa seeds induces in vivo angiogenesis via VEGF and TNF-ɑ expression and modulates in vitro doxorubicin-induced genotoxicity.

18:10 – 18:30

Closing Ceremony